By: Annabelle Clarke
May 11, 2021
Co-codamol is a complex analgesic that consists of a mild opioid, codeine phosphate and another pain medicine called acetaminophen (paracetamol). This treatment is used in cases where paracetamol alone or a combination of other anti-inflammatory drugs (NSAIDs) do not provide enough pain relief. It is also used when these medications are not advised for some patients. The combination of the different mechanisms of action present in codeine and paracetamol creates a highly effective painkiller. This is because their MOAs complement each other, which provides a long period of relief with lessened side effects.
Codeine and paracetamol work in these ways:
- Codeine phosphate is an opioid, bringing about its pain-relieving effects from attaching to opioid receptors in the brain. This activity inhibits the feeling of pain from being interpreted.
- Paracetamol belongs to the antipyretic class and works by delaying chemical massagers located in the brain that interprets pain. The medication also reduces fever associated with pain by affecting other chemical messengers that control body temperature.
Co-codamol tablets are the most effective combination therapy for pain due to their MOAs and individual efficacy. A study proved that a combination of codeine and paracetamol showed more significant results than the agents used individually. Co-codamol and alcohol should not be mixed or taken together under any circumstance. Some patients may perceive this combination as an elevated pain reliever, however, this is not true. It is advised that patients reduce their alcohol intake upon starting this treatment plan to minimise any serious adverse effect.
Patients must always read their medication label before administration. This should be done to ensure that they do not have any confirmed allergies or dangerous side effects to any of the treatment ingredients. They should also check that the right amount of the active pharmaceutical ingredient is present. In this combination treatment, the active ingredients are codeine phosphate and paracetamol. These substances are present in varying quantities.
The most common dosage ratio is co-codamol 30/500, where it contains 30mg of codeine and 500mg of paracetamol. This medication is also available in strengths of 8mg, 15mg, and 30mg of codeine, with a standard amount 500mg of paracetamol. Co-codamol 8/500 is the only strength that can be purchased without a prescription, although some established online platforms facilitate access for patients who need/have been advised to take higher doses for their treatment.
Inactive ingredients present in the medication include povidone, purified water potassium sorbate, microcrystalline cellulose, stearic acid, maize starch, talc, pregelatinised starch and magnesium stearate. These ingredients may differ in different forms of the medication. These tablets should be stored in a cool, dry area away from direct light and heat. This might affect the composition of the tablets and decrease the overall effectiveness of the treatment. This medication should also be out of the reach and sight of children as administration in children may lead to unsafe conditions.
What Is Co-codamol Used For?
Painkillers are a staple medication found in every bathroom cabinet around the world. However, these pain relievers may not be effective against certain types and severities of pain. This gives patients anxiety and a loss of hope. Paracetamol was medically used from the 1960s, while codeine was used for pain relief from the early years of the 1830s. Although these medications were effective, there were certain pains that they could not provide enough analgesia for.
Experts then decided to combine the medications, creating co-codamol tablets. The combination of these two treatments created a potent yet safe solution to various types of pain. A combination of pain relievers such as this reduces the need for multiple doses during the day, reducing co-codamol side effects.
Patients can purchase co-codamol online for the following:
- Pre-menstrual pain
- Migraines or headaches
- Post-operative pain
- Nerve pain
- Muscular pain
- Rheumatic pain
The codeine present in this medication can also assist with pain associated with constant coughing and act as a cough-suppressant. Its presence can also encourage sleep, which is therapeutic for patients who cannot get a healthy amount of sleep due to their pain.
Does Co-codamol Help You Sleep?
Opioids are a class of substances that naturally occur in the opium poppy plant. Some of these opiates are derived from this plant, such as codeine. Others are made in laboratories using the same chemical structures. These substances are usually used as pain medicines as they contain chemicals that have a relaxing effect on the body while relieving pain.
Codeine has a depressing effect on the central nervous system, which is solely responsible for its ability to relieve pain. As a result, the user becomes drowsy soon after the administration of the medication. A common side effect associated with paracetamol is also drowsiness. Since co-codamol has both these agents present, it can help sleep-deprived patients fall asleep.
When patients start their co-codamol dosage regimen, they should remember not to perform any concentration-based activities before being sure about the medication’s effects on them. For first time users, drowsiness will remain till the following day or for longer.
Is Co-codamol Strong?
The combination of paracetamol and codeine has shown strong analgesic activities in numerous studies conducted among various individuals with different types of pain. Nevertheless, patients still have their doubts since codeine is considered a ‘weak’ opioid.
A cross-sectional study included patients who had localised traumatic or inflammatory pain. The two medications used were ketorolac 15mg and 60mg/1000mg codeine/paracetamol taken orally. Two hundred patients took part in the study, randomised into the ketorolac group and the co-codamol group.
The combination of paracetamol and codeine results to be not inferior to the medication ketorolac in treating pain. However, the combination showed a significantly higher analgesic action in patients specifically with fractures and muscular pain. The study concluded that the combination is equivalent to ketorolac in certain pains, but it is superior in treating acute pains and fractures. These results play in favour of co-codamol tablets. Additionally, the use of the medication reduces the number of side effects that would have been experienced if individual agents were used.
Due to an improved side effects profile and increased efficacy rates, patients can safely buy co-codamol online to effectively treat their pain without causing any additional issues. Our platform provides information resources and access to responsive customer care channels, for further assistance.
More Helpful Information About this Product
- How Does Co-codamol Work?
- Co-codamol Dosage Guide
- Co-codamol Side Effects
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