By: Annabelle Clarke
Apr 14, 2021
This tablet also known by the brand name Imovane among others, is a sedative-hypnotic, non-benzodiazepine medication that was initially developed in the late 1980s. Commonly referred to as a Z drug, this class of medication also includes zolpidem and eszopiclone. In clinical trials, zopiclone sleeping pills have been shown to significantly reduce sleep onset latency and nighttime awakenings, while inducing negligible side effects.
Due to the known adverse effects associated with older sleeping medications, the recent trend for most patients is to use non-benzodiazepines as a first-line treatment for insomnia according to literary sources. With demonstrated efficacy and a low chance of dependence and withdrawal, non-benzodiazepines like this are currently the most frequently used sleep aids worldwide.
The pharmacological properties of zopiclone sleeping tablets include sedative, anti-anxiety and muscle relaxant effects. These effects are beneficial in the treatment of sleeping difficulties such as insomnia. This condition usually involves an inability to fall asleep (sleep onset insomnia) and stay asleep (sleep maintenance insomnia).
Exerts observe that this medication yields results by acting on the central nervous system, or CNS. Once administered, this medication enhances the activity of a neurotransmitter that occurs naturally in the body called gamma-aminobutyric acid, or GABA. The primary role of GABA is to calm down the activity of neurons in the CNS. As a result, this medication reduces anxiety, relaxes muscles and induces sleep.
A medical review that was published in 1999 took place to assess the risks and benefits of this therapeutic in 15 years of clinical experience. It found that this medication has proven effectiveness in the treatment of insomnia as well as good tolerability.
The review compared this sleep aid with various benzodiazepines, which are used to treat insomnia. It found that patients treated with Imovane reported themselves to be less affected by daytime sedation than other sleeping medications.
The review also found that, besides a bitter taste that was reported by less than 10% of study participants, this medication has an excellent safety profile. In fact, the side effect profile was found to be similar to that of placebo, which is an inactive substance that is used as a control in testing new medicines.
Common Zopiclone Side Effects
Side effects that generally affect up to 1 in 10 people are listed below. Zopiclone side effects are more likely to happen if you do not go to bed immediately after taking this medication. These side effects are, however, typically mild and improve as your body gets used to the medicine.
|Common zopiclone side effects||What can I do to manage it?|
|Bitter taste or dry mouth||Take regular sips of water and use a non-alcohol based mouthwash, particularly at bedtime.|
|Nausea or feeling sick||Rather take this medicine with or after a meal and avoid rich or spicy foods if you experience nausea during treatment.|
|Daytime tiredness||Avoid driving or participating in activities that require mental alertness until this side effect passes.|
|Dizziness||Change positions slowly to prevent dizziness. Lying down until the dizzy feeling passes may be the best option.|
|Headache||Get plenty of rest and consider using a suitable analgesic if you experience a headache. Keeping well hydrated by drinking 2 to 3 litres of water can also reduce the likelihood of developing a headache.|
By following usage and dosage instructions, the chance of zopiclone 7.5 mg side effects can be reduced considerably. Do not take more than 7.5 mg in 24 hours as this is the maximum recommended daily dose. For example, if you wake up during the night do not take a second dose to help you resume sleep.
Rare Zopiclone Side Effects
Although very highly unlikely, this medication may cause temporary memory loss in some patients. To prevent this side effect, avoid the use of this medication unless you are able to have 7 to 8 hours of uninterrupted sleep. This duration of time is required for the effects of the medication to wear off.
On rare occasions, there have been reports of people sleep walking, driving or participating in other behaviour that is out of the ordinary. They usually do not remember their behaviour upon awakening. Alcohol and certain antidepressants tend to increase the likelihood of this side effect occurring so the combination of these treatments should be avoided.
A very small percentage of people may be allergic to medications like this. Allergic reactions include symptoms such as a rash, swelling of the lips, face, throat or tongue. If you experience an allergic reaction, stop taking this medication and seek medical attention.
Other rare zopiclone side effects that may affect up to 1 in 1,000 people include confusion, irritability and shortness of breath. Due to the sedating effect of this medication, there may be an increased likelihood of falls, particularly in the elderly. For this reason, elderly patients are generally advised to take half the adult dose (3.75 mg), especially at the beginning of treatment.
No Zopiclone Side Effects Next Day
Compared with previous generation sleeping medications, non-benzodiazepines like this have distinct advantages. An unmistakable advantage is that they have a relatively brief half-life so these medications get absorbed and eliminated rapidly in the body.
The half-life of this medication is 5 to 6 hours according to medical journals. For this reason, this medication generally helps you fall asleep and stay asleep without leaving a “hangover effect” the following day. You can also order zopiclone online and have a medication with a short half-life. The elimination half-life of zopiclone is only 2.5 to 3 hours.
A clinical trial that took place to assess the next-day residual effects of this medication, found it to have an optimal effect at a 7.5 mg dose. A total of 10 healthy volunteers were involved in the trial and they received varying doses of this therapeutic that ranged from 3.75 to 7.5 mg. Various factors were measured in the study, including quantity and quality of sleep, daytime psychomotor function, reaction time and overall mood.
There were no significant impairments in complex reaction time, except at 12 hours after taking the higher dose of 10 mg. Subjective assessments by participants in the study revealed the hypnotic action of the medication was effective. The 7.5 mg dose was found to significantly improve sleep while inducing little, or no, daytime residual zopiclone side effects like drowsiness.
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- What is Zopiclone
- Zopiclone Dosage Leaflet
- How Does Zopiclone Work
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